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H Phillip Koeffler Selected Research

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8/2006Novel Gemini-vitamin D3 analog inhibits tumor cell growth and modulates the Akt/mTOR signaling pathway.

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H Phillip Koeffler Research Topics

Disease

143Neoplasms (Cancer)
01/2022 - 01/2002
31Leukemia
11/2017 - 02/2002
23Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2021 - 02/2002
22Breast Neoplasms (Breast Cancer)
01/2022 - 09/2002
19Prostatic Neoplasms (Prostate Cancer)
05/2012 - 07/2002
15Carcinogenesis
06/2022 - 02/2002
14Glioblastoma (Glioblastoma Multiforme)
01/2021 - 10/2003
13Hematologic Neoplasms (Hematological Malignancy)
10/2015 - 05/2002
12Multiple Myeloma
01/2022 - 03/2002
12Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
10/2017 - 03/2002
11Glioma (Gliomas)
01/2020 - 11/2002
10Myeloid Leukemia (Leukemia, Myelocytic)
01/2021 - 02/2003
10Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/2015 - 02/2004
9Acute Promyelocytic Leukemia
01/2021 - 10/2003
9Lung Neoplasms (Lung Cancer)
01/2019 - 01/2002
9Lymphoma (Lymphomas)
08/2012 - 05/2002
7Brain Neoplasms (Brain Tumor)
01/2018 - 11/2002
7Pancreatic Neoplasms (Pancreatic Cancer)
01/2018 - 08/2007
7BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
02/2010 - 05/2002
6Liposarcoma
02/2021 - 01/2003
6Hemochromatosis (Bronze Diabetes)
01/2016 - 08/2002
6Infections
02/2015 - 03/2008
6Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
02/2008 - 05/2004
6Endometrial Neoplasms (Endometrial Cancer)
03/2007 - 02/2004
5Hepatocellular Carcinoma (Hepatoma)
01/2017 - 09/2014
5Hypercalcemia (Milk Alkali Syndrome)
01/2014 - 11/2002
5Non-Hodgkin Lymphoma (Lymphosarcoma)
12/2009 - 02/2003
5Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
08/2009 - 03/2003
5Myelodysplastic Syndromes (Myelodysplastic Syndrome)
08/2008 - 02/2002
4Adenocarcinoma
06/2022 - 02/2009
4Esophageal Squamous Cell Carcinoma
10/2020 - 03/2007
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2018 - 09/2010
4Osteosarcoma (Osteogenic Sarcoma)
01/2018 - 01/2002
4B-Cell Lymphoma (Lymphoma, B Cell)
08/2013 - 03/2007
4Myeloproliferative Disorders (Myeloproliferative Disorder)
06/2009 - 05/2002
4Genetic Translocation (Chromosomal Translocation)
10/2007 - 05/2002
4Blast Crisis (Blast Phase)
09/2007 - 12/2003
4Philadelphia Chromosome
05/2006 - 02/2002
3Hypoxia (Hypoxemia)
01/2021 - 09/2014
3Ewing Sarcoma (Sarcoma, Ewing)
11/2020 - 01/2016
3Melanoma (Melanoma, Malignant)
01/2019 - 09/2002

Drug/Important Bio-Agent (IBA)

55Proteins (Proteins, Gene)FDA Link
01/2021 - 02/2002
26DNA (Deoxyribonucleic Acid)IBA
01/2021 - 01/2002
18Transcription Factors (Transcription Factor)IBA
01/2021 - 02/2002
18Messenger RNA (mRNA)IBA
01/2020 - 02/2002
15Pharmaceutical PreparationsIBA
01/2019 - 10/2004
15Histone Deacetylase InhibitorsIBA
01/2019 - 02/2004
14Phosphotransferases (Kinase)IBA
01/2018 - 01/2002
12LigandsIBA
09/2015 - 01/2003
12AndrogensIBA
05/2012 - 07/2002
11Tretinoin (Retinoic Acid)FDA LinkGeneric
01/2021 - 06/2003
11CCAAT-Enhancer-Binding Protein-alphaIBA
08/2012 - 02/2002
9Tyrosine Kinase InhibitorsIBA
01/2018 - 02/2002
9Vitamin DFDA LinkGeneric
01/2013 - 02/2002
8Small Interfering RNA (siRNA)IBA
01/2022 - 10/2005
8cucurbitacin BIBA
06/2013 - 09/2008
8NF-kappa B (NF-kB)IBA
02/2008 - 12/2003
7Calcitriol (Calcijex)FDA LinkGeneric
01/2014 - 03/2002
7Androgen Receptors (Androgen Receptor)IBA
10/2009 - 11/2003
7VorinostatFDA Link
02/2009 - 01/2005
7Imatinib Mesylate (Gleevec)FDA Link
08/2008 - 02/2002
7PPAR gammaIBA
01/2008 - 01/2003
7herbal preparation PC-SPESIBA
09/2007 - 09/2002
6Bortezomib (Velcade)FDA Link
02/2021 - 02/2004
6Proteasome InhibitorsIBA
02/2021 - 02/2004
6RNA (Ribonucleic Acid)IBA
01/2021 - 06/2008
6Biomarkers (Surrogate Marker)IBA
01/2019 - 07/2007
61,25-dihydroxyvitamin DIBA
05/2012 - 06/2003
5selinexorIBA
02/2021 - 09/2014
5Histones (Histone)IBA
01/2018 - 01/2006
5EnzymesIBA
08/2017 - 08/2006
5CytokinesIBA
02/2015 - 12/2003
5TriterpenesIBA
06/2013 - 10/2004
5Connective Tissue Growth FactorIBA
06/2011 - 10/2005
5OligonucleotidesIBA
09/2010 - 05/2004
5TOR Serine-Threonine KinasesIBA
08/2010 - 10/2006
4Biological ProductsIBA
12/2021 - 03/2004
4ChromatinIBA
01/2021 - 01/2005
4hydroxide ionIBA
01/2020 - 10/2005
4Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2019 - 06/2008
4Histone Deacetylases (Histone Deacetylase)IBA
03/2018 - 08/2007
4Cyclin D1IBA
01/2018 - 03/2003
4IronIBA
01/2016 - 08/2002
4GemcitabineFDA Link
09/2014 - 07/2009
4Cysteine (L-Cysteine)FDA Link
01/2014 - 08/2005
4Prostate-Specific Antigen (Semenogelase)IBA
05/2012 - 11/2003
4AgarIBA
11/2010 - 02/2004
4Cholecalciferol (Vitamin D3)FDA Link
11/2008 - 11/2002
4Human immunodeficiency virus 1 p16 proteaseIBA
08/2006 - 04/2004
4Transferrin Receptors (Transferrin Receptor)IBA
08/2005 - 02/2002
3Proteasome Endopeptidase Complex (Proteasome)IBA
02/2021 - 03/2004
3Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2020 - 07/2003
3Oncogene Proteins (Oncogene Protein)IBA
01/2019 - 03/2007
3PanobinostatIBA
01/2019 - 09/2013
3Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
03/2018 - 10/2004
3MethyltransferasesIBA
01/2018 - 01/2003
3Dasatinib (BMS 354825)FDA Link
01/2018 - 09/2013

Therapy/Procedure

48Therapeutics
01/2022 - 04/2002
9Drug Therapy (Chemotherapy)
01/2021 - 02/2003
5Aftercare (After-Treatment)
01/2017 - 09/2002